Research
What we do
We focus on key biological questions centred around host-associated microbiomes
We employ both wet lab and dry lab approaches to answer research questions. We generate and analyse large omic datasets to formulate novel targeted hypotheses (discovery science) to validate in the lab, and translate towards advancements in biotherapeutic and biotechnological applications.
How we do it
Our lab has expertise in microbial genomics (isolates and microbiomes), integrative multi-omics, and in vitro molecular microbiological techniques.
A key component of our lab’s success is also through open and collaborative science. We therefore work closely with world-leading researchers from Monash University, and with colleagues at the Salk Institute for Biological Studies, Rutgers Health New Jersey Medical School, Wellcome Sanger Institute, and the University of Melbourne to address global research challenges of mitigating infectious diseases, antimicrobial resistance, and understanding the links across microbiomes and human health.
What are we working on
Below are highlights of some current research topics in our lab:
Microbial ecology of infectious diseases
Metabolic hand-off processes driving the rebounding microbiome post-perturbation
Integrative microbiome sciences (metagenomics and metabolomics)
Pathogen colonisation of the gastrointestinal tract
Mu et al., PMID: 32817384
Microbiome signatures as predictors of host-health trajectories
Charting the microbiome response during infection
Bacterial sepsis
Mu et al., PMID: 36934086
Host microbiome responses to phage therapy
Metagenomics and metabolomics
Phage genomics
Mu et al., PMID: 33853672
We would love to hear from highly-motivated prospective graduate students, and postdoctoral scholars interested in related areas to identify and develop key questions to pursue in their research project.
Applicants must submit a concise research proposal (1 - 2 pages written) that aligns with the lab’s establshed topics and expertise to ensure appropriate support and mentoring can be provided. Please send Andre an email, and also include an up-to-date academic transcript, and a CV with at least two academic referees.